Publications

Research Articles

  1. Anamthathmakula P, Erickson JA, and Winuthayanon W. (2022) Blocking serine protease activity prevents semenogelin degradation leading to hyperviscous semen in humans. Biol Reprod. ioac023.

  2. McGlade EA, Herrera GG, Stephens KK, Olsen SLW, Winuthayanon S, Guner J, Hewitt SC, Korach KS, DeMayo FJ, Lydon JP, Monsivais D, and Winuthayanon W. (2021) Cell-type specific analysis of physiological action of estrogen in mouse oviducts. FASEB J. 35;e21563; 1-19.

  3. Hewitt SC, Carmona M, Foley G, Donoghue LJ, Lierz SL, Winuthayanon W, and Korach KS. (2020) Peri- and post-pubertal estrogen exposures of female mice optimize uterine responses later in life. Endocrinology. 161(8):1-12.

  4. Barton BE, Rock JK, Willie AM, Harris EA, Finnerty RM, Herrera GG, Anamthathmakula P, and Winuthayanon W. (2020) Serine protease inhibitor disrupts sperm motility leading to reduced fertility in female mice. Biol Reprod. 103:400-410.

  5. Griffiths RM, Pru CA, Behura SK, Cronrath AR, McCallum ML, Kelp NC, Winuthayanon W, Spencer TE, and Pru JK. (2020) AMPK is required for uterine receptivity and normal responses to steroid hormones. Reproduction. 159:707-717.

  6. Herrera GG, Lierz SL, Harris EA, Donoghue LJ, Hewitt SC, Rodriguez KF, Jefferson WN, Lydon JP, DeMayo FJ, Williams CJ, Korach KS, and Winuthayanon W. (2020) Oviductal Retention of Embryos in Female Mice Lacking Estrogen Receptor α in the Isthmus and the Uterus. Endocrinology. 161(2):1-12.

  7. Li S, Beedle MT, Herrera GB, Tam KT, and Winuthayanon W. (2019) Deletion of kallikrein 1b5 (Klk1b5) has no impact on fertility in mice. Mol Reprod & Dev. DOI: 10.1002/mrd.23145.

  8. Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ Adelman K, and Korach KS. (2018) Negative elongation factor is essential for endometrial function. FASEB J. 33(2): 3010-3023.

  9. Li S, Herrera GG, Tam KK, Lizarraga JS, Beedle M-T, Winuthayanon W. (2018) Estrogen Action in the Epithelial Cells of the Mouse Vagina Regulates Neutrophil Infiltration and Vaginal Tissue Integrity. Sci Rep. 8(11247): 1-13.

  10. Siller SS, Sharma H, Li S, Holtzman MJ, Winuthayanon W, Colognato H, Holdener B, Li F-Q, and Takemaru K-I. (2017) Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway ciliogenesis. PLoS Genetics. 13: e1007128.

  11. Li S and Winuthayanon W (2017) Collection of Post-Mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice. J Vis Exp. 129: e56670. video link.

  12. Winuthayanon W*, Lierz SL, Delarosa KC, Sampels SR, Donoghue LJ, Hewitt SC, and Korach KS (2017). Juxtacrine Activity of Estrogen Receptor α in Uterine Stromal Cells is Necessary for Estrogen-Induced Epithelial Cell Proliferation. Sci Rep. 7(8377):1-15. *corresponding author. Post-publication peer reviewed recognition in F1000 as “Very Good”, Sep 2017.

  13. Li S, Garcia M, Gewiss RL, Winuthayanon W. (2017) Crucial Role of Estrogen for the Mammalian Female in Regulating Semen Coagulation and Liquefaction in Vivo. PLoS Genetics. 13: e1006743. Featured in news outlets (sciencedaily, medicalnewstoday, phys.org, and WSU news)

  14. Li S, O’Neill SRS, Zhang Y, Holtzman MJ, Takemaru K-I, Korach KS, and Winuthayanon W. (2017). Estrogen receptor α is required for oviductal transport of embryos. FASEB J. 31: 1595-1607.

  15. Hewitt SC, Winuthayanon W, Lierz SL, Hamilton KJ, Donoghue LJ, Ramsey JT, Grimm SA, Arao Y, Korach KS. (2017) Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1. Endocrinology. 158: 2427-2435.

  16. Thongon N, Boonmuen N, Suksen K, Wichit P, Chiroungdua A, Tuchinda P, Suksamrarn A, Winuthayanon W, Piyachaturawat P. (2017) Selective estrogen receptor modulator (SERM)-like activities of diarylheptanoid, a phytoestrogen from Curcuma comosa, in breast cancer cells, pre-osteoblast cells, and rat uterine tissues. J Agric Food Chem. 65: 3490-3496.

  17. Winuthayanon W*, Bernhardt ML, Padilla-Banks E, Myers PH, Edin ML, Lih F, Korach KS, and Williams CJ*. (2015) Oviductal estrogen receptor α signaling prevents protease-mediated embryo death. eLIFE. 4: e10453. *Co-corresponding authors. NIEHS Paper of the month, Dec 2015. Highlighted in World of Reproductive Biology: The Inconstant Oviduct, Dec 2015.

  18. Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Suksamrarn A, Piyachaturawat P, Bushel PR, Korach KS. (2015) Development of phenotypic and transcriptional biomarkers to establish activity and potency of candidate xenoextrogens. Environ Health Perspect. 123: 334-52.

  19. Winuthayanon W, Hewitt SC, and Korach KS. (2014) Uterine epithelial cell ERα –dependent and –independent genomic profiles that underlie estrogen response. Biol Reprod. 95: 1-10. NIEHS paper of the month, Feb 2015.

  20. Winuthayanon W, Piyachaturawat P, Suksamrarn A, Arao Y, Burns KA, Hewitt SC, Pedersen LC, and Korach KS. (2013) Natural Estrogenic Compound Diarylheptanoid (D3): In vitro Mechanisms of Action and In Vivo Uterine Responses via Estrogen Receptor α. Environ Health Perspect. 121:433-9. NIEHS paper of the month, Jun 2013.

  21. Winuthayanon W, Hewitt SC, Orvis GD, Behringer RR, and Korach KS. (2010) Uterine epithelial estrogen receptor α is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci USA. 107: 19272-7. Post-publication peer reviewed recognition in F1000 as “must read paper”, Nov 2010, NIEHS paper of the month, Jan 2011.

  22. Winuthayanon W, Piyachaturawat P, Suksamrarn A, Ponglikitmongkol M, Arao Y, Hewitt SC, and Korach KS. (2009) Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms. Environ Health Perspect. 117: 1155-61.

  23. Winuthayanon W, Suksen K, Boonchird C, Chuncharunee A, Ponglikitmongkol M, Suksamrarn A, Piyachaturawat P. (2009) Estrogenic activity of diarylheptanoids from Curcuma comosa Roxb. requires metabolic activation. J Agric Food Chem. 57: 840-5.

Review Articles and Book Chapters

  1. McGlade EA, Miyamoto A, and Winuthayanon W. (2022) Progesterone and inflammatory response in the oviduct during physiological and pathological conditions. Cells. 11(7): 1075.

  2. Anamthathmakula P and Winuthayanon W. (2021) Prostaglandin-endoperoxide synthase 2 (PTGS2) in the oviduct: roles in fertilization and early embryo development. Endocrinology. 162: 1-14.

  3. Harris EA, Stephens KK, and Winuthayanon W. (2020) Extracellular Vesicles and the Oviduct Function. Intl J Mol Sci. 21: 8280 (p1-20).

  4. Anamthathmakula P and Winuthayanon W. (2020) Mechanism of semen liquefaction and its potential for a novel non-Hormonal contraception. Biol Reprod. 103: 411-426.

  5. Barton BE, Herrera GG, Anamthathmakula P, Rock JK, Willie AM, Harris HA, Takemaru K-I, and Winuthayanon W. (2020) Roles of steroid hormones in oviduct function. Reproduction. 159: R125-R137.

  6. Winuthayanon W and Li S. (2018) Fallopian Tube/Oviduct: Structure and Cell Biology. In: MK Skinner (ed.), Encyclopedia of Reproduction, vol. 2, 2nd ed. Academic Press, London: Elsevier. pp282-290.

  7. Olsen, LW, Li S, Winuthayanon W. (2018) Embryo Transport. In: MK Skinner (ed.), Encyclopedia of Reproduction, vol. 3, 2nd ed. Academic Press, London: Elsevier. pp357–363.

  8. Li S and Winuthayanon W. (2017) Oviduct: Roles in Fertilization and Early Embryo Development. J Endocrin. 232: R1-26.

  9. Hewitt SC, Winuthayanon W, and Korach KS. (2016) What’s new in estrogen receptor action in the female reproductive tract. J Mol Endocrin. 56: R55-71.

  10. Binder AK, Winuthayanon W, Hewitt SC, Couse JF, and Korach, KS. (2015) Steroid Receptors in the Ovary and Uterus. In: Plant TM and Zeleznik AJ (eds.), Knobil and Neill’s Physiology of Reproduction, vol. 1, 4th ed. London: Elsevier; 1099-

  11. Deroo BJ, Burns KA, Winuthayanon W, and Korach, KS. (2009) Potential effects for environmental xeno-oestrogens: Pollution and fertility. The Biochemist. 31(2):22-26. PDF